Imprimisrx’s Compounded Curcumin Emulsion

Imprimisrx’s Compounded Curcumin Emulsion

An FDA Investigation into Two Serious Adverse Events Associated with ImprimisRx’s Compounded Curcumin Emulsion Product for Injection. Two patients administered infusions of curcumin (A component of the spice turmeric) compounded with polyethylene glycol (PEG) 40 castor oil reportedly experienced immediate hypersensitivity reactions. The PEG 40 castor oil was a component of a curcumin emulsion product compounded by a pharmacy, ImprimisRx, located in Irvine, California. Hypersensitivity reactions to intravenous (IV) products containing polyethylene glycol castor oil have been reported in the literature and are the subject of warnings for a number of FDA-approved drugs. Source 2q.