Scientists reveal secrets of a deadly virus family
Scientists have solved the structure of the biological machinery used by a common virus to recognize and attack human host cells. The new structure gives scientists the first view of the glycoprotein of lymphocytic choriomeningitis virus (LCMV), present on every continent except Antarctica. The research reveals important traits in LCMV and points to possible drug targets on LCMV's close relative: Lassa virus. Ref. Source 1t.
Details of Lassa virus structure could inform development of vaccines, therapies. A 10-year Lassa virus research project has yielded structural and functional details of a key viral surface protein that could help advance development of Lassa vaccines and antibody-based therapeutics, which are currently lacking. Source 2c.