New genetic risk factor for developing autism spectrum disorder identified. A new systematic analysis has been applied to a cohort of 2,300 families who have a single child affected with autism. The study focused on identifying and characterizing low-lying genetic mutations that may have been missed in previous research, given these mutations are only present in a fraction of the bulk DNA of an individual. Source 8c.
Genetic body/brain connection identified in genomic region linked to autism. For the first time, scientists have documented a direct link between deletions in two genes--fam57ba and doc2a--in zebrafish and certain brain and body traits, such as seizures, hyperactivity, large head size, and increased fat content. Both genes reside in the 16p11.2 region of the genome, which has been linked to multiple brain and body disorders in humans, including autism spectrum disorder, developmental delays, seizures, and obesity. Source 6b.
Scientists uncover new genetic mutations linked to autism spectrum disorder. Scientists have identified mutations in a gene called CNOT1 that affect brain development and impair memory and learning. The research also revealed that CNOT1 interacts with several known autism spectrum disorder (ASD) genes, opening new research avenues for the condition. Source 4t.
Just now couples can know the likelihood of their being pregnant with a child that will be autistic so they can better prepare. Hopefully, this doesn't mean they will want abortions like the Down Syndrome test. If you know you have the genetic mutation in your DNA then simply do not have any children at all if you're not ready for the responsibility.
Links to genetic disorders in walking patterns. Researchers have linked the genetic disorders Fragile X and SHANK3 deletion syndrome -- both linked to autism and health problems -- to walking patterns by examining the microscopic movements of those wearing motion-sensored sneakers. Source 7b.
Autism-linked gene, if deleted, results in less myelin. In a new study, mice bearing a gene deletion associated with autism spectrum disorder (ASD) showed evidence of slower cognition. Another finding: cells that make myelin, a sheath around nerves that conducts electrical impulses quickly and efficiently, were diminished in the mice. This points to a mechanism that can be explored to further understand developmental disorders such as ASD. Source 8m.
The causes of autism are mostly genetic, thus, most of the risk of suffering from ASD is determined by genetic variants in our genome. In fact, it is estimated that the heritability of ASD is 80%, confirming that genetics has a greater influence than other factors on its development.