Two Americans, Briton Win Medicine Nobel Prize

- Psychology, Special Needs, Health - Posted: 8th Oct, 2007 - 1:55pm

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U.S. citizens Mario R. Capecchi and Oliver Smithies and Briton Sir Martin J. Evans won the 2007 Nobel Prize in medicine on Monday for groundbreaking stem cell discoveries that led to a technology known as gene targeting.
8th Oct, 2007 - 1:55pm / Post ID: #

Two Americans, Briton Win Medicine Nobel Prize

Congratulations to all winners. These people work very hard for the benefit of millions.

QUOTE
The process has helped scientists develop models on mice of human disorders from cardiovascular and neuro-degenerative ailments to diabetes and cancer.

The citation from the Nobel award committee said the three winners had discovered "principles for introducing specific gene modificiation in mice by the use of embryonic stem cells."

The researchers used so-called "knockout mice" - animals whose genetic code has been altered in the lab to either turn on or off certain genes that mice and humans share.

The use of gene targeting has helped expand the knowledge of "numerous genes in embryonic development, adult physiology, aging and disease," the citation said.

Capecchi, 70, was born in Verona, Italy, and moved to the United States with his mother - a Holocaust survivor - after World War II. He did work that "shed light on the cause of several human inborn malformations," the prize citation said, while Evans, 66, applied gene targeting to develop mouse models for human diseases.


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