
Scientists use CRISPR to discover Zika, dengue weaknesses
Scientists have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication. This work reveals new leads that may be useful for halting Zika, dengue and other emerging viral infections. Ref. Source 7o.
Doing the math on Zika and sex
A math professor has developed a scientific model to address the various ways the Zika virus proliferates. The study reveals that mosquito control should remain the most important mitigation method to control the virus. However, the study reveals that Zika is a complicated virus and sexual transmission increases the risk of infection and prolongs the outbreak. Ref. Source 5h.
Zika experts: Varied neurological complications, virus still detectable after recovery
The International Congress on Neuromuscular Diseases (ICND) just drew to an end in Toronto. Among the many questions addressed there were these: How diverse can the neurological complications after a Zika infection be? How long does the virus survive in the body? How is the spread of the infection developing world-wide. Ref. Source 7g.
1.6 million childbearing women could be at risk of Zika virus infection, study suggests
Research by scientists in the US and UK has estimated that up to 1.65 million childbearing women in Central and South America could become infected by the Zika virus by the end of the first wave of the epidemic. Ref. Source 7d.
Cracking the mystery of Zika virus replication
Zika virus, it is thought, can cause microcephaly, a birth defect where a baby's head is smaller than usual. Additionally, it is associated with Guillain-Barré syndrome, a neurological disorder that could lead to paralysis and even death. However, how this microbe replicates in the infected cells remains a mystery. Now, an international team has unraveled the puzzle of how Zika virus replicates. Ref. Source 9y.
Underreporting of Zika is rife; researchers project epidemic's spread in certain countries
A new study reveals a large disparity between the number of reported and projected Zika cases. The researchers, responding to a 'call to arms' to model the spread of the virus, say that while a major US outbreak isn't projected, a certain set of countries in the Americas have the right conditions for "Major outbreaks." Ref. Source 7e.
Vaccine candidates protect against Zika virus in rhesus monkeys
A ZIKV purified inactivated virus Zika vaccine candidate provided robust protection against the virus in rhesus monkeys in a new preclinical study. Findings support advancing the candidate to human trials. Ref. Source 7j.