Scientists Use Adult Stem Cell Research to Repair Damaged Corneas, Helping Blind to See
Pittsburgh, PA (LifeNews.com) -- Findings by researchers from the University of Pittsburgh School of Medicine suggest that the injection of adult stem cells from human corneas can result in restored transparency to damaged eyes. The research led by Dr. James L. Funderburgh, associate professor at the university's Department of Ophthalmology, is being heralded as a dramatic advance in stem cell research that could apply body-wide. The scientific team used adult stem cells found in the fibrous part of the eye. The cells were then injected into the damaged cornea of mice. The adult stem cells activated to reorganize the fibers and produce a transparent cornea. The study, published in the Apr. 9 journal Stem Cells, states, "The results suggest that cell-based therapy can be an effective approach to treatment of human corneal blindness.
Researchers shed light on repair mechanism for severe corneal injuries
In cases of severe ocular trauma involving the cornea, wound healing occurs following intervention, but at the cost of opaque scar tissue formation and damaged vision. Recent research has shown that mesenchymal stem cells (MSCs) — which can differentiate into a variety of cells, including bone, cartilage, muscle, and fat cells — are capable of returning clarity to scarred corneas; however, the mechanisms by which this happens remained a mystery - until now. Ref. Source 1j.