Researchers urge caution around psilocybin use
In a survey of almost 2,000 people who said they had had a past negative experience when taking psilocybin-containing 'magic mushrooms,' a researchers say that more than 10 percent believed their worst 'bad trip' had put themselves or others in harm's way, and a substantial majority called their most distressing episode one of the top 10 biggest challenges of their lives. Ref. Source 3e.
How psychedelic drug psilocybin works on brain. To see how psychedelics impact the claustrum, a mysterious region of the brain believed to control the ego, researchers compared the brain scans of people after they took psilocybin with their scans after taking a placebo. Source 2u.