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Neurodegenerative Disease

New toxic pathway identified for protein aggregates in neurodegenerative disease

Scientists have identified new processes that form protein "Clumps" that are characteristic of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). How these proteins, which can bind RNA in normal cells, stick together has remained elusive until recently, when scientists demonstrated that they demix from the watery substance inside cells, much like oil separates from water. The team sheds light onto the molecular interactions behind the process in patients with defects in the C9orf72 gene. Ref. Source 9r.

Disease Neurodegenerative

With this research we may now how to combat ALS and FTLD. Knowing a basic cause of it is a big step now as more research is done maybe we can get rid of the cause of these diseases and people can see them go away and be cured. I hope that more progress is forth coming and a cure is found.

Neurodegenerative Disease Health & Special Psychology

Researchers drill down into gene behind frontotemporal lobar degeneration. Mutations in the TMEM106B gene significantly increases a person's risk of frontotemporal lobar degeneration (FTLD), the second most common cause of dementia in those under 65, researchers have demonstrated. While the data confirmed the gene's clinical relevance, it didn't tell researchers how it caused the disease -- which is vital to developing new therapeutics. Source 3w.