This is a very important discovery. This could mean that perhaps no longer will be necessary to diagnose a child with autism based solely on observation but now physical evidence is presented.
Maternal inflammation boosts serotonin, impairs fetal brain development in mice
Fighting the flu during pregnancy sickens a pregnant woman, but it may also put the fetus at a slightly increased risk for neurodevelopmental disorders like autism later in life. A new study in pregnant mice offers a potential mechanism explaining why: Inflammation alters neurotransmitters and impairs growth of nerve cells in the developing fetal brain. Ref. Source 9x.
Largest-ever whole genome autism study yields clues on how autism-linked gene changes arise
A new study expands understanding of autism's complex causes and may hold clues for the future development of targeted treatments. The report is the largest-ever whole genome study of autism, involving 200 children with the condition and both their unaffected parents. Ref. Source 1d.
Human Forebrain Circuits Under Construction - in a Dish
Autism-related errant migration of neurons corrected in patient-derived 3D “spheroids”
National Institutes of Health (NIH)-funded neuroscientists have created a 3D window into the human brain’s budding executive hub assembling itself during a critical period in prenatal development. What’s more, they used it to discover and experimentally correct - in a petri dish - defective cell migration caused by an autism-related disorder. Ref. Source 1i.
Neuroimaging technique may help predict autism among high-risk infants. Functional connectivity magnetic resonance imaging (FcMRI) may predict which high-risk, 6-month old infants will develop autism spectrum disorder by age 2 years, according to a new study. Source 2j.
Autism severity detected with brain activity test. Children with autism have a tell-tale difference on brain tests compared with other children, researchers have found. Specifically, the researchers found that the lower a child's peak alpha frequency -- a number reflecting the frequency of certain brain waves -- the lower their non-verbal IQ was. This is the first study to highlight peak alpha frequency as a promising biomarker. Source 2e.