A newly developed vaccine against the deadly Ebola virus is "highly effective" And could help prevent its spread in the current and future outbreaks, the World Health Organization said.
Trials of the VSV-EBOV vaccine began in March in Guinea -- one of three West African nations at the center of the current outbreak -- and have shown such promise that this week it was decided to extend immediate vaccination to "All people at risk," A WHO statement said. Ref. CNN
Effectiveness Of A Herpesvirus CMV-based Vaccine Against Ebola
As the latest in a series of studies, researchers have shown the ability of a vaccine vector based on a common herpesvirus called cytomegalovirus (CMV) expressing Ebola virus glycoprotein (GP), to provide protection against Ebola virus in the experimental rhesus macaque, non-human primate (NHP) model. Demonstration of protection in the NHP model is regarded as a critical step before translation of Ebola virus vaccines into humans and other great apes.
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Ebola vaccine: Promising phase I trials
The clinical phase I trial of a potential vaccine against the dreaded Ebola virus has been successfully completed at four partner sites in Africa and Europe. The safety of the tested vaccine 'rVSV-ZEBOV', which induces persistent antibodies against the virus, has been confirmed by researchers. Ref. Source 6v.
Final trial results confirm Ebola vaccine provides high protection against disease
An experimental Ebola vaccine was highly protective against the deadly virus in a major trial in Guinea, according to results of a new study. The vaccine is the first to prevent infection from one of the most lethal known pathogens, and the findings add weight to early trial results published last year. Ref. Source 3r.
Measuring the safety, efficacy of a vaccine against Ebola virus disease
The 2014--2015 Ebola epidemic affected several countries in West Africa, leading to the death of more than 11,000 people. Although this epidemic of Ebolavirus disease is over, there is no knowing if, when or where another may strike. It is therefore more important than ever to find a reliable vaccine against this deadly disease. Research on vaccines, which was ongoing during the epidemic in West Africa, is now yielding promising results. Ref. Source 2v.