CLOVES Syndrome: Remarkable improvement in the health of 19 patients medical first. Scientists have recently demonstrated the efficacy of a novel medication in a cohort of 19 patients suffering from CLOVES Syndrome (Congenital Lipomatous Overgrowth, Vascular Malformation, Epidermal Naevi) or similar disorders. This study is an example of precision medicine and demonstrates the major benefits of this therapeutic strategy for these patients, who have seen their health and quality of life improve significantly. Source 8k.