How the immune system keeps the Epstein-Barr virus in check. A protein called PD-1, which is found on immune cells called CD8+ T cells, plays a key role in controlling infection with the Epstein-Barr virus, according to a study published May 30 in the open-access journal PLOS Pathogens by Christian Münz of the University of Zurich, and colleagues. The results from this study indicate that monitoring PD-1 signaling during future vaccination and immunotherapy studies may inform patient outcomes. Source 8z.
Genetic differences between strains of Epstein-Barr virus can alter its activity. Researchers have identified how differences in the genetic sequence of the two main strains of the cancer-associated Epstein-Barr virus (EBV) can alter the way the virus behaves when it infects white blood cells. Source 2z.
Novel therapeutic approach against Epstein-Barr virus-associated tumors. A research team hsd discovered that certain exosomes can effectively control Epstein-Barr virus-associated tumors and induce T-cell anti-tumor immunity. The novel findings provide insights into new therapeutic approach for Epstein-Barr virus (EBV)-associated tumors. Source 6n.