Fewer complications after organ transplantation. A large international study has demonstrated the safety of new cell therapy approaches for use in kidney transplant recipients. Transplant recipients were shown to require lower levels of immunosuppression in order to prevent organ rejection. This reduces the risk of side effects such as viral infections. Source 4a.
'Missing self' contributes to organ rejection after transplantation. After kidney transplantation, natural killer cells of the recipient become active because they miss 'self' proteins on donor cells. These cells contribute to organ rejection, in addition to traditional modes of rejection involving T cells and antibodies. Source 1x.