Autism-linked gene stunts developing dendrites. Increased expression of a gene linked to autism spectrum disorders (ASDs) leads to a remodeling of dendrites during brain development, according to a new study conducted in cultured neurons and an ASD mouse model. The research identifies a series of cellular and molecular events that may contribute to differences in neuronal connectivity that underlie the social and communication deficits observed in autism. Source 6m.
New causes of autism found in 'junk' DNA. Leveraging artificial intelligence techniques, researchers have demonstrated that mutations in so-called 'junk' DNA can cause autism. The study is the first to functionally link such mutations to the neurodevelopmental condition and the first clear demonstration of non-inherited, noncoding mutations causing any complex human disease or disorder. Source 5m.
Autism risk estimated at 3 to 5 percent for children whose parents have a sibling with autism. Roughly 3 to 5 percent of children with an aunt or uncle with autism spectrum disorder (ASD) can also be expected to have ASD, compared to about 1.5 percent of children in the general population, according to a new study. The findings call into question the female protective effect, a theory that females have a lower rate of ASD than males because they have greater tolerance of ASD risk factors. Source 5g.