Muscular Dystrophy - What is Duchenne Muscular Dystrophy?
Muscular dystrophy is an inherited disease. Different muscular dystrophies follow various inheritance patterns. The best-known type, Duchenne muscular dystrophy (DMD), is inherited in an X-linked recessive pattern, meaning that the mutated gene that causes the disorder is located on the X chromosome, one of the two sex chromosomes, and is thus considered sex-linked. This condition is much more common in males than in females. Ref. Source 4
New insights into muscular dystrophy point to potential treatment avenues
Certain stem cells in our bodies have the potential to turn into either fat or muscle. Experiments in mice suggest prospective drugs that manipulate these cells' fate could make it possible to relieve many of the symptoms of muscular dystrophy. Ref. Source 1o.
Human 'chimeric' cells restore crucial protein in Duchenne muscular dystrophy. Cells made by fusing a normal human muscle cell with a muscle cell from a person with Duchenne muscular dystrophy -- a rare but fatal form of muscular dystrophy -- were able to significantly improve muscle function when implanted into the muscles of a mouse model of the disease. Source 5n.